The blog explains the microbiology, diagnosis, and treatment of infections caused by anaerobic bacteria. It was was created by Itzhak Brook MD.
Infections caused by anaerobic bacteria are common, and may be serious and life-threatening. Anaerobes predominant in the bacterial flora of normal human skin and mucous membranes,and are a common cause of bacterial infections of endogenous origin. Infections due to anaerobes can evolve all body systems and sites. The predominate ones include: abdominal, pelvic, respiratory, and skin and soft tissues infections. Because of their fastidious nature, they are difficult to isolate and are often overlooked. Failure to direct therapy against these organisms often leads to clinical failures. Their isolation requires appropriate methods of collection, transportation and cultivation of specimens. Treatment of anaerobic bacterial infection is complicated by the slow growth of these organisms, which makes diagnosis in the laboratory only possible after several days, by their often polymicrobial nature and by the growing resistance of anaerobic bacteria to antimicrobial agents.
The site is made of a home page that presents new developments and pages dedicated to infectious site entities.
Kim et al. analyzed the incidence and risk factors related to mortality and assess
clinical outcomes of anaerobic bacteremia during 2012 in Yonsei University
Hospital, Seoul, Korea.
A
total of 70 anaerobic bacteria were isolated from blood of 70 bacteremia
patients. The history of cardiovascular disease as host's risk factor was
statistically significant. The incidence of anaerobic bacteremia in was 2.3% per 100 positive
blood culture patients, and the mortality rate in patients with clinically
significant anaerobic bacteremia was 21.4%. anaerobic bacteremia was frequently noted in patients with malignancy.
The
survival rate of bacteremia was significantly worse in patients who had
inappropriate therapy compared with those underwent appropriate therapy. The
most frequently isolated organism was Bacteroides fragilis (32 isolates, 46%),
Bacteroides thetaiotaomicron (10, 14%), and non-perfringens Clostridium (7,
10%).
The
World Health Organization (WHO) approved expanded use of an Israeli developed device
that allows medical workers to perform “painless circumcisions.” The PrePex
device, created by Israel-based Circ MedTech, will be granted WHO
prequalification on May 31 for use with males age 13 and above in 14 African
countries.
Circumcision
is one of the most effective ways to prevent the spread of AIDS – which affects
nearly 30 million in Africa. Research and experience shows that male
circumcision, when safely provided by well-trained health professionals,
reduces the risk of heterosexually acquired HIV infection in men by
approximately 60%. Circumcision can therefore play an important role in
preventing the spread of HIV. Persuading adult to undergo circumcision is difficult
mostly because it is painful. Furthermore surgical circumcision is done in a
hospital or specialized clinic which are not available in the countryside.
PrePex which is produced by Circ Medtech is the first and so far only
nonsurgical male circumcision device. Using the device does not require injected
anesthesia, surgery, sutures, or sterile settings. The device, consisting of
plastic and rubber rings that are placed on the penis and uses pressure to
separate the foreskin from the head of the penis. The elastic pressure ring is
applied to the foreskin, cutting off distal blood flow. The placement of PrePex
band completely separate the foreskin from the glands penis. It causes death of
all human cells within the foreskin preventing the spread of bacterial toxin or
bacterial infection from the necrotic foreskin. After a week, the foreskin
falls off, and the wound is treated with a salve.
PrePex Non Surgical Male Circumcision Procedure video
PrePex
was found in studies conducted in association with the WHO to be safe and
effective when performed by physicians and nurses, offering a virtually
bloodless procedure that requires no injection of anesthesia, no knives, no
sutures, and can be performed in a non-sterile environment. To date, more than
125,000 PrePex procedures have been conducted in 12 countries: Botswana, Kenya,
Lesotho, Malawi, Rwanda, South Africa, Swaziland, Tanzania, Uganda, Zambia,
Zimbabwe and Indonesia. More than 11 national Training Centers are located
across Africa, training local healthcare professionals.
